Ubiquinol biosynthesis

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Ubiquinol Oxidase in Acetobacter aceti

The terminal oxidase for ethanol oxidation in Acetobacter aced was purified as a complex consisting of four subunits (subunits I, II, III, and IV) with molecular masses of 72, 34, 21, and 13 kDa, respectively. Spectrophotometric analysis and catalytic properties determined with the purified enzyme showed that it belonged to a family of cytochrome a, (ba)-type ubiquinol oxidases. A polymerase ch...

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The pathway of electron flow through ubiquinol

1. Cytochrome spectra of liver and heart mitochondria incubated under various conditions are presented to compare the effects of antimycin, colletotrichin and 2-heptyl-4-hydroxyquinoline N-oxide (HQNO) additions. 2. Under aerobic conditions, in State 4, in the presence of uncoupler or in the presence of cyanide, all three inhibitors caused oxidation of cytochromes c and cl, but different change...

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Ubiquinol as adjunctive therapy of heart failure

Today in industrialized countries cardiovascular diseases are the leading cause of death. In the U.S., a significant increase in the incidence of congestive heart failure (CHF) has been found in the recent years. Researchers at the Henry Ford “Heart and Vascular Institute” in Detroit observed that the annual number of heart failure cases has more than doubled in the period from 1989 to 2012. Al...

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Ubiquinol Improves Symptoms in Children with Autism

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Myocardial energetics and ubiquinol in diastolic heart failure.

Diastolic heart failure, or heart failure with preserved ejection fraction, is a leading cause of morbidity and mortality. There are no current therapies effective in improving outcomes for these patients. The aim of this article is to review the literature and examine the role of coenzyme Q10 in heart failure with preserved ejection fraction related to mitochondrial synthesis of adenosine trip...

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ژورنال

عنوان ژورنال: Reactome - a curated knowledgebase of biological pathways

سال: 2013

ISSN: 1934-1792

DOI: 10.3180/react_160111.1